Susan S. Taylor

Susan Taylor began her career in science when she chose chemistry as her major at the Univeristy of Wisconsin, which was a bold move for a woman in 1960. During college she was determined to go to medical school, but that all changed when she met her future husband, Palmer Taylor, who was finishing his Ph.D. at the University of Wisconsin and on his way to the National Institutes of Health for post-grad work. In a history changing moment, Taylor applied to graduate school at nearby Johns Hopkins University. After her first year at Hopkins, Taylor and Palmer were married.

When Palmer was invited to join a new molecular pharmacology program in Cambridge, England, Taylor landed a fellowship at the prestigious Medical Research Council Laboratory of Molecular Biology where her love of proteins began to blossom as she worked alongside Brian Hartley.

In 1970, Taylor's fellowship at MRC ended and she accepted a fellowship with Nathan Kaplan at UC San Diego where Palmer would be as well. Not long after she began her residency at UC San Diego, she secured a faculty position in the chemistry department.

Since then Taylor has made great leaps forward in elucidating the structure, dynamics, and localization of protein kinase A (PKA). PKA is one of the cell's most important signaling molecules. It helps regulate memory, development, cell growth and cell death. Defects in PKA are associated with immune disorders and many diseases such as cancer and cardiac disorders. In 1991 Taylor and her lab solved the crystal structure of PKA's catalytic subunit which is conserved throught the kinase family. However, there was still much to be discovered and in 2005 Taylor and her colleagues were able to explain how PKA's regulatory subunit inhibits the catalytic subunit in the absence of cAMP. This discovery lead to the full understanding of how PKA works.

Education and Training
1964

B.A. Chemistry, University of Wisconsin, Madison WI

1968
Ph.D Physiological Chemistry, Johns Hopkins University, Baltimore, MD
1969-1970
Postdoctoral Fellowship, Medical Research Council Laboratory of Molecular Biology, Cambridge, England
1971-1972
Postdoctoral Fellowship, University of California, San Diego, San Diego, CA
Professional Experience
2004-Present
Professor, Department of Pharmacology
University of California, San Diego, La Jolla, CA
1997-Present
Investigator, Howard Hughes Medical Institute
1994-Present
Senior Fellow, San Diego Supercomputer Center
1985-Present
Professor, Department of Chemistry & Biochemistry
University of Caliornia, San Diego, La Jolla, CA
1987-1989
Vice Chairman (1989-Acting Chairman)
Department of Chemistry & Biochemistry
University of California, San Diego, La Jolla, CA
1980-1981
Fogarty International Fellow
Medical Research Council Laboratory of Molecular Biology
1979-1985
Associate Professor, Department of Chemistry & Biochemistry
University of California, San Diego, La Jolla, CA
1974-1979
Assistant Professor, Department of Chemistry and Biochemistry
University of California, San Diego, La Jolla CA
1972-1974
Assistant Professor in Residence, Department of Chemistry and Biochemistry
University of California, San Diego, La Jolla CA
Honors, Fellowships and Awards
2014
UCSD Chancellor's Associates Faculty Exellence Award
2014
Centenary Medal, Biochemical Society, UK
2012
Seitz Lecture, University of Chicago, IL
2011
Bard Lecture, Johns Hopkins University, MD
2010
Doty Lecture, Harvard University
2010
Assemblee des Professors, College of France, Paris, France
2009
2010 FASEB Excellence in Science Award
2009
2009 Vanderbilt Prize in Biomedical Sciences
2008
American Association for Advancement of Sciences (AAAS), Fellow
2007
ASBM William C. Rose Award
2007
Speaker for the Inaugural John C. Wriston, Jr. Memorial Lecture, University of Delaware, Newark, DE
2006
ACES Distinguished Lecturer, Case Western Reserve, Cleveland, OH
2005
Staples Lecturer, The University of Maine, Orono, Maine
2004
Varandani Lecturer, Wright State University, Dayton, OH
2004
Chauncy Leake Lecturer, University of Texas, Dalveston Medical Branch
2003
Lambersten Lecturer, University of Pennsylvania
2003
Allen Bass Lectureship, Vanderbilt University
2003
Wyeth Research Chemistry Award, Douglass College, Rutgers University, NJ
2002
UCSD Health Sciences Faculty Award of Excellence
2001
The Garvan-Olin Medal, American Chemical Society
2000
National Lecturer, The Biophysical Society
1999
Outstanding Achievement Award, Miami Winter Symposium
1998
San Diego American Chemical Society "Outstanding Scientist Award"
1998
Burroughs Welcome Visiting Professor in Pharmacology, University of North Carolina, Chapel Hill, North Carolina
1997
Elected into Institute of Medicine
1997
Elected into National Academy of Sciences
1996-2006
Merit Award, National Institute of Health
1996
The Seventh Annual Edwin G. Krebs Lecture in Molecular Pharmacology, University of Washington School of Medicine
1994
Hans Lindner Memorial Lecture, The Weizmann Institute, Rehovot, Israel
1993
Burroughs Welcome Visiting Professor, University of Utah, Salt Lake City, UT
1993
Forefronts of Large Scale Computation Award (IEEE)
1993
Earl W. Sutherland Memorial Lecturer. University of Miami School of Medicine, Miami, FL
1993
Elected into the American Academy of Arts and Sciences
1992
Burroughs Welcome Visiting Professor in Basic Medical Sciences, University of Rochester School of Medicine and Dentistry, Rochester, New York
1992
Drummond Memorial Lecturer, University of Calgary, Calgary, Alberta
1992
Distinguished Lecturer,National Jewish Center for Immunology and Respiratory Medicine, Denver, CO
1992
Faculty Distinguished Lecturer, University of California, San Diego, School of Medicine, La Jolla, CA
1992
Leslie Hellerman Memorial LEcturer, Johns Hopkins University School of Medicine, Baltimore, MD
1992
Elected into American Academy of Arts and Sciences
1991
Eli Lilly Lecturer in Biochemistry, Michigan State University, East Lansing, MI
1980-1981
Fogarty International Fellowship
1972-1977
Career Development Award NIH
1968-1971
Postdoctoral Fellowship NIH
1966-1968
Predoctoral Fellowship NIH
Professional Activities and Memberships
2010-Present
U.S. Representative/Member of the Human Frontier Sciences Program (HFSP) Council of Scientists
2010
Biomedical Science Advisory Board, Vanderbilt University School of Medicine
2010-2013
National Academy of Sciences (NAS) Governing Council
2006-2008
ASBMB Nominating Committe, Chair
2007-Present
2008 NIH Director's Pioneer Award Program, Reviewer
2007-Present
The J. Craig Ventor Institute Board of Trustees
2007-Present
California Institute for Quantitative BioScience, University of California
2001-2007
Burroughs Wellcome Fund Advisory Committee for Interfaces in Science Program (2004,Co-Chair)
2001-2006
Scientific Advisory Board for Biological Division, Los Alamos National Laboratories(LANL)
2000-2005
Council Member, National Institute of General Medical Sciences
2000-2007
Scientific Advisory Board for Burnham Institute
2000-2005
Board of Scientific Counselors, National Institute of Diabetes and Digestive and Kidney Diseases
1998-Present
Coalition for Life Sciences (CLS)
1998-Present
The David and Lucile Packard Fellowships, Advisory Panel
1997-2001
General Motors Awards Assembly
1996-2000
Member, Board of Scientific Counselors, National Cancer Institute
1995-2008
Member, Scientific Advisory Board Max-Planck-Institute fur Molekulare Physiologie, Dortmund, Germany
1994-1997
President-elect, President, past President, ASBMB
1994
Co-Chair, ASBMB Satellite Meeting on "Protein Kinases and Phosphatases"
1994
Program Chair, Annual Protein Society Meeting, San Diego
1993-1995
Vice-Chair(1993), Chair(1995), FASEB Conference on "Protein Kinases'
1993-1997
Council for Research and Clinical Investigation Awards for the American Cancer Society
1993-1998
ASBMB Representative for the Joint Steering Committee for Public Policy
1993-1997
SmithKline Beecham Pharmaceuticals Discovery Advisory Board
1992-1995
National Research Council-Commision on Life Sciences
1992-1995
Council of the Protein Society
1992
Co-Chair, ASBMB Fall Symposium on "Structure and Function of Protein Kinases and Phosphatases" Keystone, CO
1991
Co-Chair, Annual ASBMB Meeting, Atlanta, GA
1989-1992
Protein Society Nominating Committee (Chairman 1990-1992)
1989-1992
Council of American Society of Biochemistry and Molecular Biology (ASBMB)
1987-1992
Board of Scientific Councilors of National Heart, Lung and Blood Institute (Chairman 1990-1991)
1985-1991
Editorial Board, J. Biol. Chem.
1985-1986
Vice Chair (1985) abd Chairman(1986), Gordon Conference on "Second Messengers and Protein Phosphorylation"
1983-1988
American Cancer Society Study Section: Nucleic Acids and Protein Synthesis
1976-1982
NIH Biochemistry Study Section
American Society of Biologial Chemists
American Chemical Society